How do you top a multiversal meetup like the Tom Holland-Andrew Garfield-Tobey Maguire Spider-Man summit of Spider-Man: No Way Home? The official trailer for Marvel's next offering, Doctor Strange in the Multiverse of Madness, teases one way: X-Men.

The Doctor Strange sequel picks up following the events of Spider-Man: No Way Home, with Stephen Strange (Benedict Cumberbatch) suffering the consequences of having magically opened a door to the Marvel Cinematic Multiverse. What friends and foes await the good doc and Wong (Benedict Wong), along with new recruit America Chavez (Xochitl Gomez), are endless.

Which brings us to the trailer's not-so-secret cameo: 1 minute and 17 seconds into the preview, Strange is detained and led to some sort of chamber room by Ultron bots. Then… we hear an unmistakable voice say, "We should tell him the truth." That iconic voice belongs, of course, to none other than Sir Patrick Stewart, aka Professor Charles Xavier of Fox's X-Men franchise, officially crossing over into the MCU. And, Professor X is likely just the tip of the cameo iceberg.

The other big takeaway from the trailer confirms a suspicion fans have had since WandaVision ended: that Elizabeth Olsen's Wanda Maximoff, aka Scarlet Witch – in a newly unveiled costume, may not be on Strange's side. "You break the rules and become a hero. I do it and I become the enemy," she points out. "That doesn't seem fair."

Rachel McAdams is also back as Dr. Christine Palmer, as is Chiwetel Ejiofor as Mordo. Sam Raimi takes over directing duties, making his return to superhero films (Rami has not made a film in this genre since directing 2007's Spider-Man 3.)

Doctor Strange in the Multiverse of Madness hits theaters on May 6.

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